@article{67581, keywords = {Animals, Nerve Net, Action Potentials, Neurons, Male, Cues, Space Perception, Brain Mapping, Visual Cortex, Macaca fascicularis, Attention, Diffusion Tensor Imaging, Pulvinar, Cortical Synchronization}, author = {Yuri Saalmann and Mark Pinsk and Liang Wang and Xin Li and Sabine Kastner}, title = {The pulvinar regulates information transmission between cortical areas based on attention demands.}, abstract = { Selective attention mechanisms route behaviorally relevant information through large-scale cortical networks. Although evidence suggests that populations of cortical neurons synchronize their activity to preferentially transmit information about attentional priorities, it is unclear how cortical synchrony across a network is accomplished. Based on its anatomical connectivity with the cortex, we hypothesized that the pulvinar, a thalamic nucleus, regulates cortical synchrony. We mapped pulvino-cortical networks within the visual system, using diffusion tensor imaging, and simultaneously recorded spikes and field potentials from these interconnected network sites in monkeys performing a visuospatial attention task. The pulvinar synchronized activity between interconnected cortical areas according to attentional allocation, suggesting a critical role for the thalamus not only in attentional selection but more generally in regulating information transmission across the visual cortex. }, year = {2012}, journal = {Science}, volume = {337}, pages = {753-6}, month = {08/2012}, issn = {1095-9203}, doi = {10.1126/science.1223082}, language = {eng}, }